無極4註冊_歐盟評估一種由α-半乳糖苷酶和內切

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無極4註冊_歐盟評估一種由α-半乳糖苷酶和內切

    食品夥伴網訊  2021年12月13日,據歐盟食品安全局(EFSA)消息,應歐盟委員會要求,歐盟動物飼料添加劑和產品(FEEDAP)研究小組就一種由α-半乳糖苷酶(α-galactosidase)和內切-1,4-β-木聚糖酶(endo‐1,4‐β‐xylanase )組成的飼料添加劑對育肥雞、產蛋雞和小型家禽(育肥雞和產蛋雞)的安全性和有效性發表科學意見。

 
  據了解,α-半乳糖苷酶是由塔賓麴黴ATCC SD6740生產的,內切-1,4-β-木聚糖酶是由長枝木霉CBS 139997生產的。部分原文報道如下:
 
  Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Capsozyme SB Plus as a zootechnical feed additive (digestibility enhancers) for chickens for fattening, chickens reared for laying and minor poultry species (for fattening and reared for laying). The additive co ntains two enzyme ingredients (α-galactosidase, produced by a non-genetically modified strain of?Aspergillus tubingensis; and endo-1,4-β-xylanase, produced by a non-genetically modified strain of?Trichoderma longibrachiatum) and is presented in solid form. In 2020, the FEEDAP Panel issued an opinion on this product. In that assessment, the Panel co nsidered the additive safe for the target species and the environment. The Panel co ncluded that the additive does not raise co ncern for genotoxicity but could not co nclude on co nsumer safety due to the limitations identified in the 90-day toxicity study. Owing to the lack of data, the Panel could not co nclude on the potential of the additive as a skin or eye irritant nor as a skin sensitiser. Moreover, the Panel could not co nclude on the efficacy of the additive for chickens for fattening due to the limited evidence provided. The applicant provided supplementary data to support the safety for co nsumers and the efficacy of the product in chickens for fattening. The FEEDAP Panel co ncluded that the data provided support the absence of toxicological risk for the consumer. Likewise, according to the new data submitted, the FEEDAP Panel co ncluded that the additive has the potential to be efficacious in chickens for fattening at the level of 14 GALU (α-galactosidase)/18 AXC (endo-1,4-β-xylanase) per kg feed, and this co nclusion was extended to chickens reared for laying and extrapolated to minor poultry species for fattening/reared for laying.