據了解，添加劑中的兩種酶是由Talaromyces versatilis IMI 378536 and DSM 26702生產的。部分原文報道如下：

 

　　Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of ROVABIO®  ADVANCE (liquid and solid) which co ntains endo-1,4-beta-xylanase and endo-1,3(4)-beta-glucanase. The enzymes present in the additive are produced by two strains of Talaromyces versatilis, one of them genetically modified. The additive is intended to be used as a feed additive for weaned piglets and pigs for fattening. Viable cells of the production strains and DNA of the genetically modified strain were not detected in the fermentation product used to formulate the additive. ba sed on the results of a tolerance trial in weaned piglets, the FEEDAP Panel co ncluded that ROVABIO®  ADVANCE is safe for weaned piglets under the recommended co nditions of use. This co nclusion was extended to pigs for fattening. ba sed on the outcome of the toxicological studies performed, the Panel co ncluded that the additive is of no co ncern regarding co nsumer safety. ROVABIO® ADVANCE is not irritant to the skin or eyes but it is a skin and respiratory sensitiser. No risks to the enviro nment are expected from the use of the additive in animal nutrition. Owing to the lack of sufficient data, the FEEDAP Panel could not co nclude on the efficacy of ROVABIO® ADVANCE.