無極4_歐盟評估一種L-賴氨酸鹽酸鹽和 L-賴氨酸硫

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無極4_歐盟評估一種L-賴氨酸鹽酸鹽和 L-賴氨酸硫

    食品夥伴網訊  2021年12月17日,據歐盟食品安全局(EFSA)消息,應歐盟委員會要求,歐盟動物飼料添加劑和產品(FEEDAP)研究小組就谷氨酸棒桿菌CGMCC 14498生產的L-賴氨酸鹽酸鹽和 L-賴氨酸硫酸鹽(l‐lysine mo nohydrochloride and l‐lysine sulfate)作為所有動物飼料添加劑的安全性發表科學意見。

 
  經過評估,專家小組認為該添加劑對目標物種、消費者和環境都是安全的。評估中的添加劑被認為是氨基酸L-賴氨酸的有效來源。為了使補充的L-賴氨酸對反芻動物和非反芻動物同樣有效,需要防止其在瘤胃中降解。部分原文報道如下:
 
  Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-lysine mo nohydrochloride (l-lysine HCl) and l-lysine sulfate produced by Corynebacterium glutamicum (C. glutamicum) CGMCC 14498 as a nutritio nal feed additive for all animal species. The active substance is l-lysine and it is produced in two different forms (mo nohydrochloride or sulfate). The production strain C. glutamicum CGMCC 14498 and its recombinant DNA were not detected in the final products. The products l-lysine HCl and l-lysine sulfate do not pose any safety co ncern associated with the production strain. l-Lysine HCl and l-lysine sulfate produced by C. glutamicum CGMCC 14498 are co nsidered safe for the target species. When using l-lysine sulfate, the background sulfur/sulfate co ntent in the compound feed should be taken into account. l-Lysine HCl and l-lysine sulfate produced by C. glutamicum CGMCC 14498 are safe for the co nsumer and the environment. In the absence of data, the FEEDAP Panel cannot co nclude on the potential of l-lysine HCl produced by the strain C. glutamicum CGMCC 14498 to be toxic by inhalation, and on the potential of l-lysine HCl and l-lysine sulfate produced by the above-mentio ned strain to be irritant to skin or eyes, or on their potential to be dermal sensitisers. l-Lysine HCl and l-lysine sulfate produced by C. glutamicum CGMCC 14498 are co nsidered efficacious sources of the essential amino acid l-lysine for non-ruminant animal species. For the supplemental l-lysine to be as efficacious in ruminants as in non-ruminant species, this would require protection against degradation in the rumen.